Home Glossary of Ingredients Glabridine

GLABRIDINE (LICORICE ROOT EXTRACT)

GLABRIDINYL BIS-(PHYTYL SUCCINATE) or GLYCYRRHIZA GLABRA ROOT EXTRACT

Glabridin is a highly sought-after active ingredient in skincare products that target dark spots, uneven skin tone, and signs of aging. Found in licorice roots, this plant-based molecule is primarily known for its brightening and skin-evening properties. Typically encapsulated for greater stability, it acts in a targeted manner without irritating the skin. It is a cosmetic ingredient of choice for naturally enhancing the radiance of all skin tones.

A pipette dispensing liquid into an Erlenmeyer flask containing powder in a Petri dish

What Is Glabridin in Licorice? — Definition

Glabridin is an active compound found in the roots of Glycyrrhiza glabra, a plant commonly known as licorice. Used for centuries in traditional medicine, licorice is now recognized for its dermatological benefits, precisely because of its high glabridin content.

As a cosmetic active ingredient, glabridin can be encapsulated in plant-based liposomes—tiny particles that mimic cell membranes. This encapsulation protects it from oxidation, improves its penetration into the skin, and prolongs its effectiveness.

Glabridin is typically obtained through a gentle licorice extraction process that does not use harsh solvents. It is a powerful, natural active ingredient that is well tolerated by all skin types.

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Glabridine — How It Works

Glabridin from licorice acts directly on the production of melanin, the pigment responsible for skin color. It targets the enzyme tyrosinase, which is involved in melanin production, and reduces its activity, thereby lightening dark spots andevening out skin tone.

When glabridin is encapsulated, it is released gradually for sustained action. This prevents irritation and maximizes effectiveness on areas affected byhyperpigmentation.

But glabridin does more than just lighten dark spots. It is also a natural antioxidant that protects the skin from oxidative stress, which causes premature aging. It thus helps preserve the skin’s elasticity and the complexion’s radiance.

Finally, it has soothing properties: it reduces inflammatory reactions, making it a highly effective ingredient for combatingpost-inflammatory hyperpigmentation ( caused by acne, allergic reactions, sunburn, injuries, etc.).

A woman applying serum to her face with a dropper

Benefits of Glabridin for the Skin

Here are the many benefits of glabridin that make it a leading active ingredient in treatments for pigmentation spots:

✔ Brightening: It visibly reduces hyperpigmentation spots.

✔ Skin-evening: It improves the evenness and clarity of the complexion.

✔ Antioxidant: It protects the skin against free radicals.

✔ Soothing: It reduces inflammation and skin redness.

✔ Anti-aging: It slows the appearance of signs of aging.

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Is glabridin suitable for all skin types?

Yes, Glabridine is suitable for all skin types, including sensitive or reactive skin.

It is particularly recommended for skin with dark spots, an uneven complexion, or post-acne marks. It is also ideal for mature skin looking to maintain its radiance while minimizing the visible signs of aging.

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Glabridin in Cosmetics

Glabridin is primarily used in serums designed to reduce dark spots and even out skin tone, as well as in anti-aging creams and post-acne treatments. It may also be included in eye creams to reduce brown circles and dark areas under the eyes.

Contraindications and side effects:
Glabridin is well tolerated and has no known adverse effects when used in cosmetics.

Usage and application tips:
Apply topically to areas requiring skin tone evening, or to the entire face as needed, once or twice daily.

At NUHANCIAM, we have chosen glabridin for its ability to gently and effectively reduce pigmentation spots and enhance all skin tones, particularly those ranging from medium to dark.